Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Zonisamide
An antiepileptic agent that blocks voltage-dependent Na(+) channels and T-type Ca(2+) channels.
MilliporeSigma™ Calbiochem™ ZD 7288
A potent blocker of hyperpolarization-activated cyclic nucleotide-gated channels (HCN channels) in heart and brain.
MilliporeSigma™ Calbiochem™ ALDH2 Agonist, Alda-1
The ALDH2 Agonist, Alda-1, also referenced under CAS 349438-38-6, controls the biological activity of ALDH2. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ Cisplatin
Reported to sensitize glioma cells to TNF-α-induced apoptosis.
MilliporeSigma™ Calbiochem™ ADP-HPD, Dihydrate, Ammonium Salt
ADP-HPD, Dihydrate is an amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM).
MilliporeSigma™ Calbiochem™ Thrombin Substrate III, Fluorogenic
Sensitive fluorogenic substrate for the quantitative determination of thrombin.
MilliporeSigma™ Calbiochem™ Isoproterenol, Hydrochloride
Phenethylamine derivative.
MilliporeSigma™ Calbiochem™ KT5720
A potent, specific, cell-permeable, reversible and ATP-competitive inhibitor of protein kinase A (Ki = 56 nM) that is prepared by a chemical modification of K-252a.
MilliporeSigma™ Calbiochem™ KT5823
Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).
MilliporeSigma™ Calbiochem™ JAK2 Inhibitor IV
The JAK2 Inhibitor IV, also referenced under CAS 1110502-30-1, controls the biological activity of JAK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Kainic Acid
An excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21nM for 3H-kainate binding in rat striatum).
MilliporeSigma™ Calbiochem™ Kifunensine, Kitasatosporia kifunense
A potent alkaloid inhibitor of mannosidase I.